Cellucor D4 Extreme (120 Caps)

D4 Extreme may help amp up your workouts with its smooth, sustainable energy release, allowing you to support your weight loss potential and promote improved workout intensity.*

D4 Extreme

By taking advantage of the sympathetic nervous system and many neurotransmitter pathways, and by amplifying cellular ATP levels, D4 Extreme takes weight loss to a level far beyond typical weight loss supplements. D4 Extreme promotes the mobilization of fat from normal storage sites in the body and promotes fat metabolism by inducing the instinctive “fight or flight” responses that are normally triggered by the neurotransmitters adrenaline and epinephrine.

D4 Extreme has a great affinity for activating beta-adrenergic receptors. These receptors are responsible for the “fight or flight” responses that usually include enhanced oxygen use via bronchodilation, vasodilation, and increased blood flow to the muscles; increased lipolysis; and a rapid increase in cellular ATP levels via glycogenolysis. These effects maximize energy levels in the body and are induced by D4 Extreme’s active components: Emblic myrobalan extract, Octopamine, and caffeine as well as White Tea Extract to a somewhat lesser degree. The induction of these physiological responses through the activation of the adrenergic receptors is also the mechanism of action of many pharmaceutical weight loss medications.

Also noteworthy, the beta-adrenergic agonists in D4 Extreme have chemical structures that are very similar to those of certain neurotransmitters known as monoamines. Neurotransmitters in this class, as well as the active components of D4 Extreme, are quickly metabolized by the enzyme monoamine oxidase (MAO). Passion Flower Extract is another ingredient of D4 Extreme that contains a group of compounds known as beta-carbolines, which prevent the breakdown of neurotransmitters and D4 Extreme’s beta-adrenergic agonists by inhibiting MAO and acting as monoamine oxidase inhibitors (MAOIs). This action keeps the energy levels created by D4 Extreme at intense levels to give you workouts that you never thought possible. The use of Passion Flower Extract by Cellucor also ensures that a harsh energy crash does not occur and that energy levels slowly return to normal without inducing extreme fatigue as soon as your workout is finished.

D4 Extreme’s formulation also includes Green Tea and White Tea Extracts to supply the body with EGCG and ECG, two extremely potent anti-oxidants that protect against cellular damage. These active components serve as hydrogen ion (H+) donors in attacking reactive oxygen species and free radicals in the body. Upon reaction, free radicals and reactive oxygen are neutralized and can no longer induce damage to tissues, proteins, or DNA. In addition to delivering powerful anti-oxidants, Green Tea and White Tea extracts provide a variety of xanthine compounds that boost energy levels, as well as the amino acid theanine. In clinical studies, theanine has been shown to relieve stress, promote relaxation, and improve cognitive function. Additional benefits of theanine include increased neurotransmitter synthesis and an immune system boost brought about by an enhancement of the ability to combat foreign pathogens.

Another active component of D4 Extreme, Evodiamine, promotes weight loss at a cell-signaling level. Evodiamine induces the sustained activation of a protein known as ERK, which reduces the genetic signal for the production of PPAR-?. In fat cells, PPAR-? is the regulatory protein that is responsible for the formation of new fat cells. While some other Cellucor products simply inhibit PPAR-? signaling, Evodiamine acts to prevent PPAR-? synthesis and, thus, effectively suppresses the body’s ability to form new fat cells.

D4 Extreme is also formulated with Sclareolide, a compound that rapidly increases cellular energy (ATP) levels. Sclareolide is an activator of adenylyl cyclase, a G-type protein that is found on the cell surface and is responsible for converting ATP into cyclic-AMP (cAMP). This conversion results in a sudden increase in cAMP, which signals the cells to synthesize more ATP and causes a sudden energy increase in all cells of the body.

Through synergist actions that use the pathways and receptors also used by neurotransmitters, supply unique anti-oxidants, and elevate overall metabolic energy levels, D4 Extreme elevates the energy levels and fat loss experienced during your workouts.

also works to help with appetite regulation.* With more than 10 years of R&D, it is no surprise that D4 Extreme has become renowned as one of the best fat burners around.